![Tumor-intrinsic and -extrinsic roles of c-Kit: mast cells as the primary off-target of tyrosine kinase inhibitors | Oncogene Tumor-intrinsic and -extrinsic roles of c-Kit: mast cells as the primary off-target of tyrosine kinase inhibitors | Oncogene](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fonc.2010.494/MediaObjects/41388_2011_Article_BFonc2010494_Fig1_HTML.jpg)
Tumor-intrinsic and -extrinsic roles of c-Kit: mast cells as the primary off-target of tyrosine kinase inhibitors | Oncogene
![The KIT receptor tyrosine kinase. (A) C-KIT mutations occur in 80 –90%... | Download Scientific Diagram The KIT receptor tyrosine kinase. (A) C-KIT mutations occur in 80 –90%... | Download Scientific Diagram](https://www.researchgate.net/publication/51031327/figure/fig3/AS:305865690238985@1449935471527/The-KIT-receptor-tyrosine-kinase-A-C-KIT-mutations-occur-in-80-90-of-GISTs.png)
The KIT receptor tyrosine kinase. (A) C-KIT mutations occur in 80 –90%... | Download Scientific Diagram
![Src Family Kinases Are Involved in the Differential Signaling from Two Splice Forms of c-Kit - ScienceDirect Src Family Kinases Are Involved in the Differential Signaling from Two Splice Forms of c-Kit - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0021925819712861-gr1.jpg)
Src Family Kinases Are Involved in the Differential Signaling from Two Splice Forms of c-Kit - ScienceDirect
![The SCF/c‐KIT system in the male: Survival strategies in fertility and cancer - Cardoso - 2014 - Molecular Reproduction and Development - Wiley Online Library The SCF/c‐KIT system in the male: Survival strategies in fertility and cancer - Cardoso - 2014 - Molecular Reproduction and Development - Wiley Online Library](https://onlinelibrary.wiley.com/cms/asset/3a542ff7-3070-4932-8c0a-f85b893e3a36/mrd22430-fig-0001-m.jpg)
The SCF/c‐KIT system in the male: Survival strategies in fertility and cancer - Cardoso - 2014 - Molecular Reproduction and Development - Wiley Online Library
![Stem Cell Factor Receptor/c-Kit: From Basic Science to Clinical Implications | Physiological Reviews Stem Cell Factor Receptor/c-Kit: From Basic Science to Clinical Implications | Physiological Reviews](https://journals.physiology.org/cms/10.1152/physrev.00046.2011/asset/images/medium/z9j0041226280003.jpeg)
Stem Cell Factor Receptor/c-Kit: From Basic Science to Clinical Implications | Physiological Reviews
![Figure 3 from Receptor tyrosine kinase (c-Kit) inhibitors: a potential therapeutic target in cancer cells | Semantic Scholar Figure 3 from Receptor tyrosine kinase (c-Kit) inhibitors: a potential therapeutic target in cancer cells | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/6082b71d882e2f2c2db82516f60effe72ae30183/9-Figure3-1.png)
Figure 3 from Receptor tyrosine kinase (c-Kit) inhibitors: a potential therapeutic target in cancer cells | Semantic Scholar
![A holistic view on c-Kit in cancer: Structure, signaling, pathophysiology and its inhibitors - ScienceDirect A holistic view on c-Kit in cancer: Structure, signaling, pathophysiology and its inhibitors - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0304419X21001293-gr2.jpg)
A holistic view on c-Kit in cancer: Structure, signaling, pathophysiology and its inhibitors - ScienceDirect
Role and significance of c-KIT receptor tyrosine kinase in cancer: A review | Biomolecules and Biomedicine
![A survival Kit for pancreatic beta cells: stem cell factor and c-Kit receptor tyrosine kinase | SpringerLink A survival Kit for pancreatic beta cells: stem cell factor and c-Kit receptor tyrosine kinase | SpringerLink](https://media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs00125-015-3504-0/MediaObjects/125_2015_3504_Fig2_HTML.gif)
A survival Kit for pancreatic beta cells: stem cell factor and c-Kit receptor tyrosine kinase | SpringerLink
![Mast cell cKIT (CD117) receptor structure. Note: KIT receptor, a class... | Download Scientific Diagram Mast cell cKIT (CD117) receptor structure. Note: KIT receptor, a class... | Download Scientific Diagram](https://www.researchgate.net/publication/334371020/figure/fig1/AS:779130501079041@1562770595078/Mast-cell-cKIT-CD117-receptor-structure-Note-KIT-receptor-a-class-III-RTK-includes.png)
Mast cell cKIT (CD117) receptor structure. Note: KIT receptor, a class... | Download Scientific Diagram
![Distinct cellular properties of oncogenic KIT receptor tyrosine kinase mutants enable alternative courses of cancer cell inhibition | PNAS Distinct cellular properties of oncogenic KIT receptor tyrosine kinase mutants enable alternative courses of cancer cell inhibition | PNAS](https://www.pnas.org/cms/10.1073/pnas.1610179113/asset/eabf3edf-0c91-4675-90d6-a8f8f4bf0f0b/assets/graphic/pnas.1610179113fig01.jpeg)
Distinct cellular properties of oncogenic KIT receptor tyrosine kinase mutants enable alternative courses of cancer cell inhibition | PNAS
![Figure 1 from Receptor tyrosine kinase (c-Kit) inhibitors: a potential therapeutic target in cancer cells | Semantic Scholar Figure 1 from Receptor tyrosine kinase (c-Kit) inhibitors: a potential therapeutic target in cancer cells | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/6082b71d882e2f2c2db82516f60effe72ae30183/5-Figure1-1.png)
Figure 1 from Receptor tyrosine kinase (c-Kit) inhibitors: a potential therapeutic target in cancer cells | Semantic Scholar
![Tumor-intrinsic and -extrinsic roles of c-Kit: mast cells as the primary off-target of tyrosine kinase inhibitors | Oncogene Tumor-intrinsic and -extrinsic roles of c-Kit: mast cells as the primary off-target of tyrosine kinase inhibitors | Oncogene](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fonc.2010.494/MediaObjects/41388_2011_Article_BFonc2010494_Fig3_HTML.jpg)
Tumor-intrinsic and -extrinsic roles of c-Kit: mast cells as the primary off-target of tyrosine kinase inhibitors | Oncogene
![Figure 2 from Receptor tyrosine kinase (c-Kit) inhibitors: a potential therapeutic target in cancer cells | Semantic Scholar Figure 2 from Receptor tyrosine kinase (c-Kit) inhibitors: a potential therapeutic target in cancer cells | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/6082b71d882e2f2c2db82516f60effe72ae30183/9-Figure2-1.png)
Figure 2 from Receptor tyrosine kinase (c-Kit) inhibitors: a potential therapeutic target in cancer cells | Semantic Scholar
![The D816V mutation in the catalytic domain of the c-Kit receptor downstream tyrosine kinase in peripheral blood mononuclear cells (by M. Niedoszytko). The D816V mutation in the catalytic domain of the c-Kit receptor downstream tyrosine kinase in peripheral blood mononuclear cells (by M. Niedoszytko).](https://s3-eu-west-1.amazonaws.com/ppreviews-plos-725668748/2631302/preview.jpg)
The D816V mutation in the catalytic domain of the c-Kit receptor downstream tyrosine kinase in peripheral blood mononuclear cells (by M. Niedoszytko).
![Structure of c-Kit. The extracellular domain of c-Kit is comprised of... | Download Scientific Diagram Structure of c-Kit. The extracellular domain of c-Kit is comprised of... | Download Scientific Diagram](https://www.researchgate.net/publication/7296397/figure/fig2/AS:340773485727745@1458258138068/Structure-of-c-Kit-The-extracellular-domain-of-c-Kit-is-comprised-of-five-immunoglobulin.png)