![Transactivation Assays that Identify Indirect and Direct Activators of Human Pregnane X Receptor (PXR, NR1I2) and Constitutive Androstane Receptor (CAR, NR1I3) | Bentham Science Transactivation Assays that Identify Indirect and Direct Activators of Human Pregnane X Receptor (PXR, NR1I2) and Constitutive Androstane Receptor (CAR, NR1I3) | Bentham Science](https://www.eurekaselect.com/images/graphical-abstract/dml/11/2/007.jpg)
Transactivation Assays that Identify Indirect and Direct Activators of Human Pregnane X Receptor (PXR, NR1I2) and Constitutive Androstane Receptor (CAR, NR1I3) | Bentham Science
![Role of Nuclear Receptors PXR and CAR in Xenobiotic-Induced Hepatocyte Proliferation and Chemical Carcinogenesis. | Semantic Scholar Role of Nuclear Receptors PXR and CAR in Xenobiotic-Induced Hepatocyte Proliferation and Chemical Carcinogenesis. | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/c340df88bd4109bc328d364b4370363c22988876/7-Figure5-1.png)
Role of Nuclear Receptors PXR and CAR in Xenobiotic-Induced Hepatocyte Proliferation and Chemical Carcinogenesis. | Semantic Scholar
![Identification of Chemical Modulators of the Constitutive Activated Receptor (CAR) in a Gene Expression Compendium - Keiyu Oshida, Naresh Vasani, Carlton Jones, Tanya Moore, Susan Hester, Stephen Nesnow, Scott Auerbach, David R. Identification of Chemical Modulators of the Constitutive Activated Receptor (CAR) in a Gene Expression Compendium - Keiyu Oshida, Naresh Vasani, Carlton Jones, Tanya Moore, Susan Hester, Stephen Nesnow, Scott Auerbach, David R.](https://journals.sagepub.com/cms/10.1621/nrs.13002/asset/images/large/10.1621_nrs.13002-fig10.jpeg)
Identification of Chemical Modulators of the Constitutive Activated Receptor (CAR) in a Gene Expression Compendium - Keiyu Oshida, Naresh Vasani, Carlton Jones, Tanya Moore, Susan Hester, Stephen Nesnow, Scott Auerbach, David R.
![P450 Induction in Cryopreserved Hepatocytes from PXR and CAR Nuclear Receptor Knock-out Rats Poster | Technology Networks P450 Induction in Cryopreserved Hepatocytes from PXR and CAR Nuclear Receptor Knock-out Rats Poster | Technology Networks](https://assets.technologynetworks.com/production/dynamic/images/content/305171/p450-induction-in-cryopreserved-hepatocytes-from-pxr-and-car-nuclear-receptor-knock-out-rats-305171-960x540.jpg?cb=9711929)
P450 Induction in Cryopreserved Hepatocytes from PXR and CAR Nuclear Receptor Knock-out Rats Poster | Technology Networks
![Inhibition of pregnane X receptor pathway contributes to the cell growth inhibition and apoptosis of anticancer agents in ovarian cancer cells Inhibition of pregnane X receptor pathway contributes to the cell growth inhibition and apoptosis of anticancer agents in ovarian cancer cells](https://www.spandidos-publications.com/article_images/ijo/49/3/IJO-49-03-1211-g06.jpg)
Inhibition of pregnane X receptor pathway contributes to the cell growth inhibition and apoptosis of anticancer agents in ovarian cancer cells
![The constitutive androstane receptor and pregnane X receptor in the brain - Torres‐Vergara - 2020 - British Journal of Pharmacology - Wiley Online Library The constitutive androstane receptor and pregnane X receptor in the brain - Torres‐Vergara - 2020 - British Journal of Pharmacology - Wiley Online Library](https://bpspubs.onlinelibrary.wiley.com/cms/asset/74375e25-5283-4f0d-8790-6f9481185326/bph15055-fig-0001-m.jpg)
The constitutive androstane receptor and pregnane X receptor in the brain - Torres‐Vergara - 2020 - British Journal of Pharmacology - Wiley Online Library
![Distinct Roles of the Sister Nuclear Receptors PXR and CAR in Liver Cancer Development | Drug Metabolism & Disposition Distinct Roles of the Sister Nuclear Receptors PXR and CAR in Liver Cancer Development | Drug Metabolism & Disposition](https://dmd.aspetjournals.org/content/dmd/50/7/1019/F1.large.jpg)
Distinct Roles of the Sister Nuclear Receptors PXR and CAR in Liver Cancer Development | Drug Metabolism & Disposition
![Profiling Drug Activity of Human and Ortholog Xenobiotic-Sensing Receptors: PXR, CAR, AhR, and FXR - INDIGO Biosciences Profiling Drug Activity of Human and Ortholog Xenobiotic-Sensing Receptors: PXR, CAR, AhR, and FXR - INDIGO Biosciences](https://indigobiosciences.com/wp-content/uploads/2017/03/SOT-2017-Poster_Ortholog-Xenobiotic-receptor-activity-profiling-KT_FINAL-1024x658.png)
Profiling Drug Activity of Human and Ortholog Xenobiotic-Sensing Receptors: PXR, CAR, AhR, and FXR - INDIGO Biosciences
![JCI - A novel panel of mouse models to evaluate the role of human pregnane X receptor and constitutive androstane receptor in drug response JCI - A novel panel of mouse models to evaluate the role of human pregnane X receptor and constitutive androstane receptor in drug response](https://dm5migu4zj3pb.cloudfront.net/manuscripts/35000/35483/medium/JCI0835483.f1.jpg)
JCI - A novel panel of mouse models to evaluate the role of human pregnane X receptor and constitutive androstane receptor in drug response
![PDF] Regulatory network of lipid-sensing nuclear receptors: roles for CAR, PXR, LXR, and FXR. | Semantic Scholar PDF] Regulatory network of lipid-sensing nuclear receptors: roles for CAR, PXR, LXR, and FXR. | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/ad2c14a52306333ff08c5b63c14e63ce8f08c6ab/4-Figure3-1.png)
PDF] Regulatory network of lipid-sensing nuclear receptors: roles for CAR, PXR, LXR, and FXR. | Semantic Scholar
![Species-specific regulation of PXR/CAR/ER-target genes in the mouse and rat liver elicited by o, p'-DDT | BMC Genomics | Full Text Species-specific regulation of PXR/CAR/ER-target genes in the mouse and rat liver elicited by o, p'-DDT | BMC Genomics | Full Text](https://media.springernature.com/lw685/springer-static/image/art%3A10.1186%2F1471-2164-9-487/MediaObjects/12864_2008_Article_1680_Fig5_HTML.jpg)
Species-specific regulation of PXR/CAR/ER-target genes in the mouse and rat liver elicited by o, p'-DDT | BMC Genomics | Full Text
![Targeting xenobiotic receptors PXR and CAR for metabolic diseases: Trends in Pharmacological Sciences Targeting xenobiotic receptors PXR and CAR for metabolic diseases: Trends in Pharmacological Sciences](https://www.cell.com/cms/attachment/2007960841/2030645141/gr1.jpg)
Targeting xenobiotic receptors PXR and CAR for metabolic diseases: Trends in Pharmacological Sciences
![A novel nuclear xenobiotic receptors (AhR/PXR/CAR)-mediated mechanism of DEHP-induced cerebellar toxicity in quails (Coturnix japonica) via disrupting CYP enzyme system homeostasis - ScienceDirect A novel nuclear xenobiotic receptors (AhR/PXR/CAR)-mediated mechanism of DEHP-induced cerebellar toxicity in quails (Coturnix japonica) via disrupting CYP enzyme system homeostasis - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0269749117304074-gr6.jpg)
A novel nuclear xenobiotic receptors (AhR/PXR/CAR)-mediated mechanism of DEHP-induced cerebellar toxicity in quails (Coturnix japonica) via disrupting CYP enzyme system homeostasis - ScienceDirect
![Establishing Transcriptional Signatures to Differentiate PXR-, CAR-, and AhR-Mediated Regulation of Drug Metabolism and Transport Genes in Cryopreserved Human Hepatocytes | Journal of Pharmacology and Experimental Therapeutics Establishing Transcriptional Signatures to Differentiate PXR-, CAR-, and AhR-Mediated Regulation of Drug Metabolism and Transport Genes in Cryopreserved Human Hepatocytes | Journal of Pharmacology and Experimental Therapeutics](https://jpet.aspetjournals.org/content/jpet/365/2/262/F4.large.jpg)
Establishing Transcriptional Signatures to Differentiate PXR-, CAR-, and AhR-Mediated Regulation of Drug Metabolism and Transport Genes in Cryopreserved Human Hepatocytes | Journal of Pharmacology and Experimental Therapeutics
![PXR in zebrafish: preliminary RNA-Seq analysis. SRP Project 5: Developmental Toxicity of non-Dioxin-like PCBs and Chemical Mixtures John Stegeman, PI. - ppt download PXR in zebrafish: preliminary RNA-Seq analysis. SRP Project 5: Developmental Toxicity of non-Dioxin-like PCBs and Chemical Mixtures John Stegeman, PI. - ppt download](https://images.slideplayer.com/24/7234304/slides/slide_6.jpg)